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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HCFC1 All Species: 11.21
Human Site: S1557 Identified Species: 22.42
UniProt: P51610 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51610 NP_005325.2 2035 208732 S1557 S S T G E P S S G Q E S A G S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001088011 1702 173511 G1250 A M A R S S M G A G E P R T A
Dog Lupus familis XP_867443 2039 208943 S1560 S S T G D P S S G Q E P T S S
Cat Felis silvestris
Mouse Mus musculus Q61191 2045 210519 S1566 S S T G D P S S G Q E P T T S
Rat Rattus norvegicus Q5RKG2 723 79130 T271 V P H K G E N T E N S P H D C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509058 2033 207643 Q1544 A P V E P P G Q E T P S P A V
Chicken Gallus gallus XP_001234928 787 86020 G335 Y I W S G R D G Y R K A W N N
Frog Xenopus laevis NP_001087989 2101 219049 E1599 P M D S A V P E H N A A E L H
Zebra Danio Brachydanio rerio Q7ZUV7 1173 122182 V721 S T H D A P P V V H L I S S R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V4C8 1500 160166 L1048 T S S S A S A L F T G G D T A
Honey Bee Apis mellifera XP_624189 1550 166762 S1098 I E A S E E A S M P D A M E L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791039 1216 126587 T764 A N S S G V T T K L V T I P I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 82.3 93.8 N.A. 93.7 24.2 N.A. 82.4 26.3 68.8 20.4 N.A. 33 34.2 N.A. 37
Protein Similarity: 100 N.A. 82.5 95 N.A. 95.5 30 N.A. 86 32.2 76.6 33.1 N.A. 47.5 50.2 N.A. 46.5
P-Site Identity: 100 N.A. 6.6 73.3 N.A. 73.3 0 N.A. 13.3 0 0 13.3 N.A. 6.6 13.3 N.A. 0
P-Site Similarity: 100 N.A. 20 80 N.A. 80 13.3 N.A. 20 26.6 6.6 26.6 N.A. 33.3 33.3 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 0 17 0 25 0 17 0 9 0 9 25 9 9 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % C
% Asp: 0 0 9 9 17 0 9 0 0 0 9 0 9 9 0 % D
% Glu: 0 9 0 9 17 17 0 9 17 0 34 0 9 9 0 % E
% Phe: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % F
% Gly: 0 0 0 25 25 0 9 17 25 9 9 9 0 9 0 % G
% His: 0 0 17 0 0 0 0 0 9 9 0 0 9 0 9 % H
% Ile: 9 9 0 0 0 0 0 0 0 0 0 9 9 0 9 % I
% Lys: 0 0 0 9 0 0 0 0 9 0 9 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 9 0 9 9 0 0 9 9 % L
% Met: 0 17 0 0 0 0 9 0 9 0 0 0 9 0 0 % M
% Asn: 0 9 0 0 0 0 9 0 0 17 0 0 0 9 9 % N
% Pro: 9 17 0 0 9 42 17 0 0 9 9 34 9 9 0 % P
% Gln: 0 0 0 0 0 0 0 9 0 25 0 0 0 0 0 % Q
% Arg: 0 0 0 9 0 9 0 0 0 9 0 0 9 0 9 % R
% Ser: 34 34 17 42 9 17 25 34 0 0 9 17 9 17 25 % S
% Thr: 9 9 25 0 0 0 9 17 0 17 0 9 17 25 0 % T
% Val: 9 0 9 0 0 17 0 9 9 0 9 0 0 0 9 % V
% Trp: 0 0 9 0 0 0 0 0 0 0 0 0 9 0 0 % W
% Tyr: 9 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _